Research

Recent Publications

A new transcriptional role for matrix metalloproteinase-12 in antiviral immunity. Marchant DJ, Bellac CL, Moraes TJ, Wadsworth SJ, Dufour A, Butler GS, Bilawchuk LM, Hendry RG, Robertson AG, Cheung CT, Ng J, Ang L, Luo Z, Heilbron K, Norris MJ, Duan W, Bucyk T, Karpov A, Devel L, Georgiadis D, Hegele RG, Luo H, Granville DJ, Dive V, McManus BM, Overall CM.  Nat Med. 2014 Apr 28; PMID: 24784232 [PubMed – as supplied by publisher]

Effectiveness of educational interventions on asthma self-management in punjabi and chinese asthma patients: a randomized controlled trial.Poureslami I, Nimmon L, Doyle-Waters M, Rootman I, Schulzer M, Kuramoto L, Fitzgerald JM.J Asthma. 2012 Jun;49(5):542-51.PMID: 22715910 [PubMed – in process]Related citations

The “Lost NNT” can be used to represent uncertainty surrounding number needed to treat. Sadatsafavi M, Ganjizadeh S, Hatala R, Marra C, Fitzgerald M. J Clin Epidemiol. 2012 May 30. [Epub ahead of print] PMID: 22652350 [PubMed – as supplied by publisher] Related citations

MRM-based multiplexed quantitation of 67 putative cardiovascular disease biomarkers in human plasma. Domanski D, Percy AJ, Yang J, Chambers AG, Hill JS, Freue GV, Borchers CH. Proteomics. 2012 Apr;12(8):1222-43. doi: 10.1002/pmic.201100568. PMID: 22577024 [PubMed – in process] Related citations

White blood cell differentials enrich whole blood expression data in the context of acute cardiac allograft rejection. Shannon CP, Hollander Z, Wilson-McManus J, Balshaw R, Ng RT, McMaster R, McManus BM, Keown PA, Tebbutt SJ. Bioinform Biol Insights. 2012;6:49-61. Epub 2012 Apr 10. PMID: 22550401 [PubMed – in process] Free PMC Article Related citations

Canadian Thoracic Society 2012 guideline update: diagnosis and management of asthma in preschoolers, children and adults. Lougheed MD, Lemiere C, Ducharme FM, Licskai C, Dell SD, Rowe BH, Fitzgerald M, Leigh R, Watson W, Boulet LP; Canadian Thoracic Society Asthma Clinical Assembly. Can Respir J. 2012 Mar-Apr;19(2):127-64. PMID: 22536582 [PubMed – in process] Related citations

Canadian Cohort Obstructive Lung Disease (CanCOLD): Fulfilling the Need for Longitudinal Observational Studies in COPD. Bourbeau J, Tan WC, Benedetti A, Aaron SD, Chapman KR, Coxson HO, Cowie R, Fitzgerald M, Goldstein R, Hernandez P, Leipsic J, Maltais F, Marciniuk D, O’Donnell D, Sin DD, For The Cancold Study Group. COPD. 2012 Mar 20. [Epub ahead of print] PMID: 22433011 [PubMed – as supplied by publisher] Related citations

Does this patient with liver disease have cirrhosis? Udell JA, Wang CS, Tinmouth J, FitzGerald JM, Ayas NT, Simel DL, Schulzer M, Mak E, Yoshida EM. JAMA. 2012 Feb 22;307(8):832-42. PMID: 22357834 [PubMed – indexed for MEDLINE] Related citations

Peripheral blood gene expression changes during allergen inhalation challenge in atopic asthmatic individuals. Kam SH, Singh A, He JQ, Ruan J, Gauvreau GM, O’Byrne PM, Fitzgerald JM, Tebbutt SJ. J Asthma. 2012 Apr;49(3):219-26. Epub 2012 Feb 9. PMID: 22316092 [PubMed – indexed for MEDLINE] Related citations

A guide to the translation of the Global Initiative for Asthma (GINA) strategy into improved care. Boulet LP, FitzGerald JM, Levy ML, Cruz AA, Pedersen S, Haahtela T, Bateman ED. Eur Respir J. 2012 May;39(5):1220-9. Epub 2012 Jan 26. PMID: 22282546 [PubMed – in process] Related citations

Three months of rifapentine and isoniazid for latent tuberculosis infection. Sterling TR, Villarino ME, Borisov AS, Shang N, Gordin F, Bliven-Sizemore E, Hackman J, Hamilton CD, Menzies D, Kerrigan A, Weis SE, Weiner M, Wing D, Conde MB, Bozeman L, Horsburgh CR Jr, Chaisson RE; TB Trials Consortium PREVENT TB Study Team. N Engl J Med. 2011 Dec 8;365(23):2155-66. PMID: 22150035 [PubMed – indexed for MEDLINE] Related citations

Effects of a short course of inhaled corticosteroids in noneosinophilic asthmatic subjects. Lemière C, Tremblay C, FitzGerald M, Aaron SD, Leigh R, Boulet LP, Martin JG, Nair P, Olivenstein R, Chaboillez S. Can Respir J. 2011 Sep-Oct;18(5):278-82. PMID: 21969930 [PubMed – indexed for MEDLINE] Related citations

Republished editorial: Targeting lung attacks. FitzGerald JM. Postgrad Med J. 2011 Oct;87(1032):655-6 PMID: 21954030 [PubMed] Related citations

Genetics of sputum gene expression in chronic obstructive pulmonary disease. Qiu W, Cho MH, Riley JH, Anderson WH, Singh D, Bakke P, Gulsvik A, Litonjua AA, Lomas DA, Crapo JD, Beaty TH, Celli BR, Rennard S, Tal-Singer R, Fox SM, Silverman EK, Hersh CP; ECLIPSE Investigators. PLoS One. 2011;6(9):e24395. Epub 2011 Sep 16. PMID: 21949713 [PubMed – indexed for MEDLINE] Related citations

In two parallel pragmatic equivalence trials, leukotriene receptor antagonists as initial therapy for asthma compared with inhaled corticosteroids and as add on therapy to ICS compared with adding long-acting β agonists provided equivalent short-term asthma quality of life but were associated with more medication switches. FitzGerald JM. Evid Based Med. 2012 Apr;17(2):44-5. Epub 2011 Sep 26. PMID: 21949261 [PubMed] Related citations

Antibiotic consumption in children prior to diagnosis of asthma. Marra F, Marra CA, Richardson K, Lynd LD, Fitzgerald MJ. BMC Pulm Med. 2011 May 31;11:32. PMID: 21627795 [PubMed – indexed for MEDLINE] Related citations

Targeting lung attacks. FitzGerald JM. Thorax. 2011 May;66(5):365-6. Epub 2011 Mar 11 PMID: 21398372 [PubMed – indexed for MEDLINE] Related citations

Commonplace to condemned: The discovery that tobacco kills, and how Richard Doll shaped modern smoking cessation practices. Andrew J. Juren, MD, Jiri Frohlich, MD, FRCPC, Andrew Ignaszewski, MD, FRCPC. Issue: BCMJ, Vol. 54, No. 4, May 2012, page(s) 183-188 Articles

Normal-Range Blood Lactate Concentration in Septic Shock is Prognostic and Predictive. Wacharasint P, Nakada TA, Boyd JH, Russell JA, Walley KR. Shock. 2012 May 1;. [Epub ahead of print] PMID: 22552014 [PubMed – as supplied by publisher]

Detectable clonal mosaicism from birth to old age and its relationship to cancer. Laurie CC, Laurie CA, Rice K, Doheny KF, Zelnick LR, McHugh CP, Ling H, Hetrick KN, Pugh EW, Amos C, Wei Q, Wang LE, Lee JE, Barnes KC, Hansel NN, Mathias R, Daley D, Beaty TH, Scott AF, Ruczinski I, Scharpf RB, Bierut LJ, Hartz SM, Landi MT, Freedman ND, Goldin LR, Ginsburg D, Li J, Desch KC, Strom SS, Blot WJ, Signorello LB, Ingles SA, Chanock SJ, Berndt SI, Le Marchand L, Henderson BE, Monroe KR, Heit JA, de Andrade M, Armasu SM, Regnier C, Lowe WL, Hayes MG, Marazita ML, Feingold E, Murray JC, Melbye M, Feenstra B, Kang JH, Wiggs JL, Jarvik GP, McDavid AN, Seshan VE, Mirel DB, Crenshaw A, Sharopova N, Wise A, Shen J, Crosslin DR, Levine DM, Zheng X, Udren JI, Bennett S, Nelson SC, Gogarten SM, Conomos MP, Heagerty P, Manolio T, Pasquale LR, Haiman CA, Caporaso N, Weir BS. Nat Genet. 2012 May 6;. [Epub ahead of print] PMID: 22561516 [PubMed – as supplied by publisher]

The Relationship between Telomere Length and Mortality in Chronic Obstructive Pulmonary Disease (COPD). Lee J, Sandford AJ, Connett JE, Yan J, Mui T, Li Y, Daley D, Anthonisen NR, Brooks-Wilson A, Man SF, Sin DD. PLoS One. 2012;7(4):e35567. PMID: 22558169 [PubMed – in process]

Quantitative assessment of forward and backward second harmonic three dimensional images of collagen Type I matrix remodeling in a stimulated cellular environment. Thomas Abraham, Damian Kayra, Bruce McManus, Alex Scott. . Available online 15 May 2012.

miR-33a modulates ABCA1 expression, cholesterol accumulation, and insulin secretion in pancreatic islets. Wijesekara N, Zhang LH, Kang MH, Abraham T, Bhattacharjee A, Warnock GL, Verchere CB, Hayden MR. Diabetes 2012 Mar;61(3):653-8. Epub 2012 Feb 7.PMID:22315319[PubMed – indexed for MEDLINE] PMCID:PMC3282802[Available on 2013/3/1].

THE CARDIO-PULMONARY EFFECTS OF VASOPRESSIN COMPARED TO NOREPINEPHRINE IN SEPTIC SHOCK. Gordon AC, Wang N, Walley KR, Ashby D, Russell JA. Chest. 2012 Apr 19;. [Epub ahead of print] PMID: 22518026 [PubMed – as supplied by publisher]

Circulating angiopoietin and Tie-2 levels in systemic sclerosis. Dunne JV, Keen KJ, Van Eeden SF. Rheumatol Int. 2012 Mar 30;. [Epub ahead of print] PMID: 22461185 [PubMed – as supplied by publisher]

A common polymorphism in the 5′ region of the human protein c gene binds USF1. Thain KR, Nakada TA, Boyd JH, Russell JA, Walley KR. Thromb Res. 2012 Mar 16. [Epub ahead of print]  PMID: 22425321 [PubMed – as supplied by publisher]

Emphysema in an adult with galactosialidosis linked to a defect in primary elastic fiber assembly. Lehman A, Mattman A, Sin D, Pare P, Zong Z, d’Azzo A, Campos Y, Sirrs S, Hinek A. Mol Genet Metab. 2012 Feb 8.

Lipid-bound apolipoproteins in tyrosyl radical-oxidized HDL stabilize ABCA1 like lipid-free apolipoprotein A-I. Hossain MA, Ngeth S, Chan T, Oda MN, Francis GA. BMC Biochem. 2012 Jan 16;13(1):1. [Epub ahead of print]

Mechanical properties of asthmatic airway smooth muscle. Chin LY, Bosse Y, Pascoe C, Hackett TL, Seow CY, Pare PD. Eur Respir J. 2012 Jan 20. [Epub ahead of print]

Force oscillations simulating breathing maneuvers do not prevent force adaptation. Pascoe C, Jiao Y, Seow CY, Pare PD, Bosse Y. American Journal of Respiratory Cell and Molecular Biology.

Cost-effective prediction of gender-labeling errors and estimation of gender-labeling error rates in candidate-gene association studies. Qu C, Schuetz JM, Min JE, Leach S, Daley D, Spinelli JJ, Brooks-Wilson A, Graham J. Front Genet. 2011;2:31. PMID: 22303327 [PubMed – in process]

Mapping of the Wnt/β-Catenin/TCF Response Elements in the Human Versican Promoter. Rahmani M, Carthy JM, McManus BM. Methods Mol Biol. 2012;836:35-52. PMID: 22252626

The airway epithelium nucleotide-binding domain and leucine-rich repeat protein 3 inflammasome is activated by urban particulate matter. Hirota JA, Hirota SA, Warner SM, Stefanowicz D, Shaheen F, Beck PL, Macdonald JA, Hackett TL, Sin DD, Van Eeden S, Knight DA. J Allergy Clin Immunol. 2012 Jan 7.

Inflammation in myocardial diseases. Marchant DJ, Boyd JH, Lin DC, Granville DJ, Garmaroudi FS, McManus BM. Circ Res. 2012 Jan 6;110(1):126-44. PMID: 22223210

Induction of Endothelial Nitric Oxide Synthase Expression by IL-17 in Human Vascular Endothelial Cells: Implications for Vascular Remodeling in Transplant Vasculopathy. Liu AC, Lee M, McManus BM, Choy JC. J Immunol. 2012 Jan 4. PMID: 22219320

Immune and non-immune functions of the immunoproteasome. Angeles A, Fung G, Luo H. Front Biosci. 2012 Jan 1;17:1904-16.

Genetic association between human chitinases and lung function in COPD. Aminuddin F, Akhabir L, Stefanowicz D, Paré PD, Connett JE, Anthonisen NR, Fahy JV, Seibold MA, Burchard EG, Eng C, Gulsvik A, Bakke P, Cho MH, Litonjua A, Lomas DA, Anderson WH, Beaty TH, Crapo JD, Silverman EK, Sandford AJ. Hum Genet. 2011 Dec 28.

ABCA1-dependent mobilization of lysosomal cholesterol requires functional Niemann-Pick C2 but not Niemann-Pick C1 protein. Boadu E, Nelson RC, Francis GA. Biochim Biophys Acta. 2011 Dec 10. [Epub ahead of print]

Three months of rifapentine and isoniazid for latent tuberculosis infection. Sterling TR, Villarino ME, Borisov AS, Shang N, Gordin F, Bliven-Sizemore E, Hackman J, Hamilton CD, Menzies D, Kerrigan A, Weis SE, Weiner M, Wing D, Conde MB, Bozeman L, Horsburgh CR Jr, Chaisson RE; TB Trials Consortium PREVENT TB Study Team. N Engl J Med. 2011 Dec 8;365(23):2155-66. PMID: 22150035 [PubMed – indexed for MEDLINE] Related citations

Neutrophil-Mediated Lung Damage: A New COPD Phenotype? Sin D, van Eeden SF. Respiration. 2011 Dec 6. PMID: 22142967

Genetic association between human chitinases and lung function in COPD. Aminuddin F, Akhabir L, Stefanowicz D, Paré PD, Connett JE, Anthonisen NR, Fahy JV, Seibold MA, Burchard EG, Eng C, Gulsvik A, Bakke P, Cho MH, Litonjua A, Lomas DA, Anderson WH, Beaty TH, Crapo JD, Silverman EK, Sandford AJ. Hum Genet. 2011 Dec 2

2011 Consensus statement on endomyocardial biopsy from the Association for European Cardiovascular Pathology and the Society for Cardiovascular Pathology. Leone O, Veinot JP, Angelini A, Baandrup UT, Basso C, Berry G, Bruneval P, Burke M, Butany J, Calabrese F, d’Amati G, Edwards WD, Fallon JT, Fishbein MC, Gallagher PJ, Halushka MK, McManus B, Pucci A, Rodriguez ER, Saffitz JE, Sheppard MN, Steenbergen C, Stone JR, Tan C, Thiene G, van der Wal AC, Winters GL. Cardiovasc Pathol. 2011 Dec 1. PMID: 22137237

Occupational exposure influences on gender differences in respiratory health. Dimich-Ward H, Beking K, Dybuncio A, Chan-Yeung M, Du W, Karlen B, Camp PG, Kennedy SM. Lung 2011 Nov 15.

The immunity-related gtpase irgm3 relieves endoplasmic reticulum stress response during coxsackievirus b3 infection via a pi3k/akt dependent pathway. Liu Z, Zhang HM, Yuan J, Ye X, Taylor GA, Yang DC. Cell Microbiol 2011.

WNT3A induces a contractile and secretory phenotype in cultured vascular smooth muscle cells that is associated with increased gap junction communication. Carthy JM, Luo Z, McManus BM. Lab Invest. 2011 Nov 21. PMID: 22105568

Inotropes and vasopressors: more than hemodynamics! Bracht H, Calzia E, Georgieff M, Singer J, Radermacher P, Russell JA. Br J Pharmacol. 2011 Nov 10. doi: 10.1111/j.1476-5381.2011.01776.x.

The protective role of tlr6 in a mouse model of asthma is mediated by il-23 and il-17a. Moreira AP, Cavassani KA, Ismailoglu UB, Hullinger R, Dunleavy MP, Knight DA, Kunkel SL, Uematsu S, Akira S, Hogaboam CM. J Clin Invest 2011 Nov 1;121(11):4420-32. doi: 10.1172/JCI44999.

Minimally invasive multiphoton and harmonic generation imaging of extracellular matrix structures in lung airway and related diseases. Abraham T, Hirota JA, Wadsworth S, Knight DA. Pulm Pharmacol Ther. 2011 Oct;24(5):487-96.

The Semantic Automated Discovery and Integration (SADI) Web service Design-Pattern, API and Reference Implementation. Wilkinson MD, Vandervalk B, McCarthy L. J Biomed Semantics. 2011 Oct 24;2(1):8.

IL17A genetic variation is associated with altered susceptibility to Gram-positive infection and mortality of severe sepsis. Nakada TA, Russell JA, Boyd JH, Walley KR. Crit Care. 2011 Oct 25;15(5):R254.

Regulatable stiffness in relaxed airway smooth muscle: A target for asthma treatment? Raqeeb A, Jiao Y, Syyong HT, Pare PD, Seow CY. J Appl Physiol. 2011 Oct 13.

Targeting endothelial dysfunction in vascular complications associated with diabetes. Sharma A, Bernatchez PN, de Haan JB. Int J Vasc Med 2012;2012:750126.

Opposite effects of allergy prevention depending on CD14 rs2569190 genotype in 3 intervention studies. Kerkhof M, Daley D, Postma DS, Park JE, Chan Yeung M, Wijga AH, Gehring U, de Jongste JC, Smit HA, Brunekreef B, van Schayck OC, Becker A, Koppelman GH. J Allergy Clin Immunol. 2011 Oct 12.

Incidence of pancreatitis, secondary causes, and treatment of patients referred to a specialty lipid clinic with severe hypertriglyceridemia: a retrospective cohort study. Sandhu S, Al-Sarraf A, Taraboanta C, Frohlich J, Francis GA. Lipids Health Dis 2011;10:157 (1-7).

Molecular signatures of end-stage heart failure. Lin D, Hollander Z, Meredith A, Stadnick E, Sasaki M, Cohen Freue G, Qasimi P, Mui A, Ng RT, Balshaw R, Wilson-McManus JE, Wishart D, Hau D, Keown PA, McMaster R, McManus BM. J Card Fail. 2011 Oct;17(10):867-74.

Lysosomal Acid Lipase Deficiency Impairs Regulation of ABCA1 and Formation of High Density Lipoproteins in Cholesterol Ester Storage Disease. Kristin L. Bowden, Nicolas J. Bilbey, Leanne M. Bilawchuk, Emmanuel Boadu, Rohini Sidhu, Daniel S. Ory, Hong Du, Teddy Chan, and Gordon A. Francis. J Biol Chem 2011;286:30624-35.

Smoking kills, quitting heals: the importance of smoking cessation in COPD. Park HY, Sin D. Clin Respir J. 2011 Oct;5(4):185-6. doi: 10.1111/j.1752-699X.2011.00270.x.

Confirmed Swine-Origin Influenza A(H1N1) Viral Pneumonia: Computed Tomographic Findings in the Immunocompetent and the Immunocompromised. Chandler TM, Leipsic J, Nicolaou S, Quiney B, Romney M, Müller NL, Ajlan AM. J Comput Assist Tomogr. 2011 Sep-Oct;35(5):602-7.

Changes in forced expiratory volume in 1 second over time in COPD. Vestbo J, Edwards LD, Scanlon PD, Yates JC, Agusti A, Bakke P, Calverley PM, Celli B, Coxson HO, Crim C, Lomas DA, MacNee W, Miller BE, Silverman EK, Tal-Singer R, Wouters E, Rennard SI; ECLIPSE Investigators. N Engl J Med. 2011 Sep 29;365(13):1184-92. Epub 2011 Sep 26.

A Successful 4S Heart Transplantation. Al-Mohaissen MA, Ignaszewski AP, Cheung A, Kaan A, Chiu W, Kealy J, Virani SA. Can J Cardiol. 2011 Sep 21.

The innate and adaptive immune response induced by alveolar macrophages exposed to ambient particulate matter. Miyata R, van Eeden SF. Toxicol Appl Pharmacol. 2011 Sep 17.

Gender differences in symptoms of myocardial ischaemia. Mackay MH, Ratner PA, Johnson JL, Humphries KH, Buller CE. Eur Heart J. 2011 Sep 14.

A ‘Good’ muscle in a ‘Bad’ environment: The importance of airway smooth muscle force adaptation to airway hyperresponsiveness. Bosse Y, Chapman DG, Pare PD, King GG, Salome CM. Respir Physiol Neurobiol. 2011 Sep 14

Serpina3n attenuates granzyme B-mediated decorin cleavage and rupture in a murine model of aortic aneurysm. Ang LS, Boivin WA, Williams SJ, Zhao H, Abraham T, Carmine-Simmen K, McManus BM, Bleackley RC, Granville DJ. Cell Death Dis. 2011 Sep 8;2:e209. doi: 10.1038/cddis.2011.88.

Diagnostic performance of high-definition coronary computed tomography angiography performed with multiple radiation dose reduction strategies. Heydari B, Leipsic J, Mancini GB, Min JK, Labounty T, Taylor C, Freue GV, Heilbron B. Can J Cardiol. 2011 Sep;27(5):606-12.

The TLR9 ligand CpG-C attenuates acute inflammatory cardiac dysfunction. Mathur S, Walley KR, Boyd JH. Shock. 2011 Sep 7.

Effects of a short course of inhaled corticosteroids in noneosinophilic asthmatic subjects. Lemière C, Tremblay C, FitzGerald M, Aaron SD, Leigh R, Boulet LP, Martin JG, Nair P, Olivenstein R, Chaboillez S. Can Respir J. 2011 Sep-Oct;18(5):278-82. PMID: 21969930 [PubMed – indexed for MEDLINE] Related citations

Republished editorial: Targeting lung attacks. FitzGerald JM. Postgrad Med J. 2011 Oct;87(1032):655-6 PMID: 21954030 [PubMed] Related citations

Defective function at the epithelial junction: A novel therapeutic frontier in asthma? Knight DA, Stick SM, Hackett TL. J Allergy Clin Immunol. 2011 Sep;128(3):557-8.

Is Atherosclerotic Heart Disease in COPD a Distinct Phenotype? Man SF, Leipsic JA, Man JP, Sin DD. Chest. 2011 Sep;140(3):569-71.

Identification of nucleolin as a cellular receptor for human respiratory syncytial virus. Tayyari F, Marchant D, Moraes TJ, Duan W, Mastrangelo P, Hegele RG. Nat Med. 2011 Aug 14;17(9):1132-5. doi: 10.1038/nm.2444.

Dual organism transcriptomics of airway epithelial cells interacting with conidia of Aspergillus fumigatus. Oosthuizen JL, Gomez P, Ruan J, Hackett TL, Moore MM, Knight DA, Tebbutt SJ. PLoS One. 2011;6(5):e20527. Epub 2011 May 31.

Vascular endothelial growth factor-D is overexpressed in human cardiac allograft vasculopathy and diabetic atherosclerosis and induces endothelial permeability to low-density lipoproteins in vitro. Wong BW, Wong D, Luo H, McManus BM. J Heart Lung Transplant. 2011 Aug;30(8):955-62. Epub 2011 May 28.

Wnt3a induces myofibroblast differentiation by upregulating TGF-β signaling through SMAD2 in a β-catenin-dependent manner. Carthy JM, Garmaroudi FS, Luo Z, McManus BM. PLoS One. 2011;6(5):e19809. Epub 2011 May 18.

Effect of gene environment interactions on lung function and cardiovascular disease in COPD. Hackett TL, Stefanowicz D, Aminuddin F, Sin DD, Connett JE, Anthonisen NR, Paré PD, Sandford AJ. Int J Chron Obstruct Pulmon Dis. 2011;6:277-87. Epub 2011 May 10.

Health literacy, language, and ethnicity-related factors in newcomer asthma patients toCanada: a qualitative study. Poureslami IRootman I, Doyle-Waters MMNimmon L, Fitzgerald JM. Immigr Minor Health. 2011 Apr; 13(2):315-22.

Using community-based participatory research (CBPR) with ethno-cultural groups as a tool to develop culturally and linguistically appropriate asthma educational material. Poureslami, Iraj; Nimmon, Laura; Doyle-Waters, Mary Madeleine Rita; FitzGerald, J Mark Diversity in Health and Care, Volume 8, Number 4, March 2011 , pp. 203-215(13)

Granzyme B contributes to extracellular matrix remodeling and skin aging in apolipoprotein E knockout mice. Hiebert PR, Boivin WA, Abraham T, Pazooki S, Zhao H, Granville DJ. Exp Gerontol. 2011 Jun;46(6):489-99. Epub 2011 Feb 18.