Executive Committee

Bruce McManus

Bruce McManus is Professor, Department of Pathology and Laboratory Medicine, the University of British Columbia. He serves as Co-Director of the Institute for Heart + Lung Health, Director of the James Hogg Research Centre at St. Paul’s Hospital and as Director of the NCE CECR Centre of Excellence for Prevention of Organ Failure (PROOF Centre). Dr. McManus served as the inaugural Scientific Director of the Institute of Circulatory and Respiratory Health, Canadian Institutes of Health Research, from December 2000 until April 2006.
Dr. McManus received BA and MD degrees at the University of Saskatchewan, an MSc in Applied Physiology from Pennsylvania State University, and PhD in Exercise Physiology and Biochemistry from the University of Toledo.  He pursued post-doctoral fellowships in Environmental Physiology at the University of California – Santa Barbara and in Cardiovascular and Pulmonary Pathology at the National Heart, Lung, and Blood Institute in Bethesda, MD.  Residency training at the Peter Bent Brigham Hospital – Harvard University in Internal Medicine and Pathology, was followed by specialization in Cardiovascular Pathology.  After 11 years as a faculty member at the University of Nebraska Medical Centre, including a sabbatical as John F. Fogarty Senior International Fellow at the Max Planck Institute for Biochemistry, Martinsried, Germany, Dr. McManus joined the Faculty of Medicine of the University of British Columbia as Department Head of Pathology and Laboratory Medicine in July 1993, a post he held until December, 2000. Dr. McManus is a Fellow of the Royal College of Physicians and Surgeons of Canada, the College of American Pathologists, the American College of Cardiology, and the American College of Chest Physicians.

Dr. McManus’ basic and clinical investigative program is focused on mechanisms, consequences, detection and prevention of injury and aberrant repair involved in inflammatory diseases of the heart and blood vessels, with particular emphasis on enteroviral infections of the heart and transplant vascular disease. He works in a cross-disciplinary setting on translational research questions for which answers are critically enabled by computational sciences including biomarker discovery and validation, information acquisition, annotation, and use, and registry development to support heart and lung research. Dr. McManus has co-authored ~350 peer-reviewed publications, as well as many chapters.  He has edited four books. He is co-holder of numerous patents. He has served as Councilor for the International Society for Heart Research and for the American Society for Investigative Pathology. He is past-president of the Society for Cardiovascular Pathology. He currently serves on editorial boards of several professional and scientific journals, and on many advisory committees and boards. He has long been committed to training and mentoring scientist trainees across a range of disciplines.  He has convened many public and private sector partnerships in research.

Dr. McManus has been recognized for his scientific contributions by numerous institutions and organizations through visiting professorships and lectureships. He was co-recipient of the prestigious Max Planck Research Award in 1991.  He was elected to the Royal Society of Canada as a Fellow of the Academy of Sciences in 2002.  He received a UBC Killam Research Prize – Senior Scientist Category in 2003.  In 2005, he was elected as an inaugural Fellow of the Canadian Academy of Health Sciences and was honoured with the Research Achievement Award of the Canadian Cardiovascular Society. In 2006 Dr. McManus received the BC Innovation Council’s Lieutenant Governor’s Technology Innovation Award. He has been honored with the 2007 UBC Distinguished Medical Lecturer Award and 2008 David F. Hardwick Lifetime Achievement Award.  He was awarded the 2009 CSATVB Scientific Excellence Award, Canadian Society for Atherosclerosis, Thrombosis and Vascular Biology. Dr. McManus has been recognized by the Society for Cardiovascular Pathology with the 2010 Distinguished Achievement Award and by Providence Health Care with the 2010 Research & Mission Award. Recently, he received the 2011 Sarrazin Award Lecture from the Canadian Physiological Society.

Education / Training:

  • University of Saskatchewan BA Biology and Physical Education 1963-1967
  • Pennsylvania State University MSc Exercise Physiology 1967-1969
  • University of Toledo PhD Exercise Physiology and Biochemistry 1969-1972
  • University of Saskatchewan MD Medicine 1973-1977

Extra-Degree Training And Experience:

  • University of Saskatchewan, Saskatoon, SK, Canada; President of Students’ Physical Education Association, 1966-67; Research Assistant in Child Growth and Development Study, 1966-67
  • Pennsylvania State University, State College, PA; Teaching Graduate Assistant, 1967-68
  • University of Toledo, Toledo, OH; Teaching and Research Graduate Assistant, 1968-71
  • University of California, Santa Barbara, CA, Institute of Environmental Stress; Postgraduate Research Physiologist, 1971-73
  • University of Saskatchewan, Saskatoon, SK, Canada, Medical Student, 1973-77; President of Student Medical Society, 1976-77; Saskatchewan Medical Association Joint Committee on Internship Training, 1976-77; Cardiology and Cardiovascular Pathology electives at University of California, San Diego, 1976
  • Harvard University, Peter Bent Brigham Hospital, Boston, MA, Clinical Fellow in Medicine, Medical House Officer, 1977-78; Clinical Fellow and Resident in Anatomic Pathology 1978-80; Cardiovascular Pathology elective, Children’s Hospital Medical Center (Drs. Van Praagh), 1979
  • Somerville Hospital, Somerville, MA, Emergency Room Medical Casualty Officer, 1978-80
  • National Heart, Lung and Blood Institute, Bethesda, MD, Pathology Branch, Senior Staff Fellow, 1980-82
  • American University, Washington DC, Visiting Professor, College of Graduate Studies, Winter-Spring 1982
  • Max Plank Institute for Biochemistry, Martinsried, Germany, John F. Fogarty Senior Fellow, 1989-90